<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2026 Workiva-->
<!--r:019c7151-75ac-7e95-83b8-91d798a15d98,g:2d4f87c4-74e3-4fae-8b1d-8d22755083ad-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.medline.com/role/Cover" xlink:type="simple" xlink:href="mdln-20260225.xsd#Cover"/>
  <link:presentationLink xlink:role="http://www.medline.com/role/Cover" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_019c7151-75ac-703d-a65b-23e9c5e79217" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_DocumentType_019c7151-75ac-703d-a65b-23e9c5e79217" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_019c7151-75ac-77bc-8774-516e4a121d03" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_DocumentPeriodEndDate_019c7151-75ac-77bc-8774-516e4a121d03" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_019c7151-75ac-730d-89bc-406566e33b33" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_EntityRegistrantName_019c7151-75ac-730d-89bc-406566e33b33" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_019c7151-75ac-751e-b0c8-3a9947e76989" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_EntityIncorporationStateCountryCode_019c7151-75ac-751e-b0c8-3a9947e76989" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_019c7151-75ac-7324-8722-956e0e651aa1" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_EntityFileNumber_019c7151-75ac-7324-8722-956e0e651aa1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_019c7151-75ac-776b-a6ac-8ec2b0261cd8" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_EntityTaxIdentificationNumber_019c7151-75ac-776b-a6ac-8ec2b0261cd8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_019c7151-75ac-7563-b901-8cb31ca12413" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_EntityAddressAddressLine1_019c7151-75ac-7563-b901-8cb31ca12413" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_019c7151-75ac-7a63-8a04-5ff8536a5887" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_EntityAddressCityOrTown_019c7151-75ac-7a63-8a04-5ff8536a5887" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_019c7151-75ac-7e07-b686-6d71b5836fd8" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_EntityAddressStateOrProvince_019c7151-75ac-7e07-b686-6d71b5836fd8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_019c7151-75ac-7f69-9392-e91d296d223c" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_EntityAddressPostalZipCode_019c7151-75ac-7f69-9392-e91d296d223c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_019c7151-75ac-7bba-85c0-7b274b9bf8ca" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_CityAreaCode_019c7151-75ac-7bba-85c0-7b274b9bf8ca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_019c7151-75ac-77cd-aa8f-68dbc0e73206" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_LocalPhoneNumber_019c7151-75ac-77cd-aa8f-68dbc0e73206" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_WrittenCommunications_019c7151-75ac-78c4-a6ab-5216612d9add" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_WrittenCommunications"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_WrittenCommunications_019c7151-75ac-78c4-a6ab-5216612d9add" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SolicitingMaterial_019c7151-75ac-76a2-ba82-9c03a3725daf" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_SolicitingMaterial"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_SolicitingMaterial_019c7151-75ac-76a2-ba82-9c03a3725daf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementTenderOffer_019c7151-75ac-7734-90bf-51ea890047dd" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_PreCommencementTenderOffer"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_PreCommencementTenderOffer_019c7151-75ac-7734-90bf-51ea890047dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_019c7151-75ac-7aac-8f81-668c1f4908f7" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_PreCommencementIssuerTenderOffer"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_019c7151-75ac-7aac-8f81-668c1f4908f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_019c7151-75ac-712b-b320-d11064d28560" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_Security12bTitle_019c7151-75ac-712b-b320-d11064d28560" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_019c7151-75ac-78c5-b848-c0ddcc48703f" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_TradingSymbol_019c7151-75ac-78c5-b848-c0ddcc48703f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_019c7151-75ac-7660-8a5f-dc3eaf043c4d" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_SecurityExchangeName_019c7151-75ac-7660-8a5f-dc3eaf043c4d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_019c7151-75ac-7eb1-a419-057fa2082728" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_EntityEmergingGrowthCompany_019c7151-75ac-7eb1-a419-057fa2082728" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_019c7151-75ac-787f-8070-8c72546ea155" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_EntityCentralIndexKey_019c7151-75ac-787f-8070-8c72546ea155" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_019c7151-75ac-792a-85f3-b458fd2d6c79" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_019c7151-75ac-7174-a3fb-cd39d0ed87d2" xlink:to="loc_dei_AmendmentFlag_019c7151-75ac-792a-85f3-b458fd2d6c79" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
